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Altogether, these proinflammatory changes in vascular homeostasis are known to promote proatherogenic accumulation of both inflammatory leukocytes and LDL in the vascular wall 36 (Fig

Exerts cytoprotective effects by blocking pro-apoptotic Bax protein, reduces oxidative stress, and supports cellular energy production

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however, the review noted that most included studies focused on patients with diabetes rather than those with obesity